Facilities and EquipmentOur
facilities at Process NMR Associates are located at 87A Sand Pit Rd, Danbury, CT 06810.
Directions to PNA.
.
 Liquid-State NMR Equipment:Process NMR Associates (PNA) owns and
operates two Varian Mercury-300 superconducting NMR spectrometers. The computer system comprise
of Sun Blade
workstations operating with VNMR 6.1C. All computers are locally networked to the PNA intranet. The spectrometer
probes comprise of a Varian 5 mm 4-nucleus probe which is a dual band probe
simultaneously tuned to 1H/19F
and 31P/13C
and a broad band 5mm probe with PFG.
Other Varian 5mm broadband probes are available,
 along
with
Varian broadband 10mm probe for 13C and low sensitivity experiments, as well as a Nalorac 20 mm probe for short
13C experimental times. Full variable
temperature capabilities are also available. For a listing of possible applications
see the liquid-state NMR
applications page.
Solid-State NMR Equipment: Process NMR Associates
also operates a
solid-state Varian UnityPlus-200 NMR
spectrometer. The solid-state NMR probe is a 7mm Doty Scientific Supersonic
CP/MAS probe capable of observing any NMR active nucleus (excluding low gyromagnetic ratio nuclei), using either single pulse, multi-pulse, or cross
polarization in conjunction with magic angle spinning (at rates up to 13 kHz).
For a listing of possible applications see the solid-state NMR applications
page. A Varian 5mm broadband probe is also available if liquid-state NMR is
required at this lower field. A high temperature accessory is utilized for
high temperature applications and a spin-rate controller is used to keep MAS
spin speed rates constant.
Solid-state NMR applications.
Mercury System Magnets - Alox and R2D2
 
Mercury MVX-300-PFG NMR System
Mercury-300 NMR system
Our NMR systems all utilize the Varian "R2D2" magnet - take a look inside one
of these magnets - Deconstruction
Process NMR Equipment:
Process NMR Associates also operates 3 process NMR units for model or
application development and feasibility testing. The three systems are
permenant magnet systems operating at slightly different magnetic fields.
- The oldest system (circa 1994) is a "B"-type magnet, facilitating a 1/4"
process flow probe or a lab probe and operating at 53 MHz.
- The "C" type magnet system (circa 1999) is three generations of development
beyond the old system and operates at 57.8 MHz. This system is used for low
viscosity applications at lower temperatures (ambient to ~60oC).
Again process probes and lab probes can be used in NMR studies.
- The third system is a "D" type system which is favored in high temperature
applications (up to 120oC). The magnet bore on this system is larger
and can facilitate a 3/8" process probe which is adequately dewared to isolate
the magnet pole faces from the stream temperature. This system operates at 58.3
MHz. This system is equipped with a variable temperature process probe that
allows studies of viscous materials up to 100oC
- A fourth high resolution 60 MHz NMR from Aspect Italia SRL was added in
October 2011 and represents the state-of-the-art process NMR spectrometer.
PNA will be developing online and at-line applications for this platform
under contract
- Process NMR Applications
Permanent Magnet NMR Systems Lab - Process NMR Associates - 60 MHz
HR-NMR and 20 MHz TD-NMR
Time-Domain NMR Spectrometers at 14, 16, 19.5, 20 and 25 MHz
Process NMR Associates operates a total of 5 TD-NMR spectrometers. We have an
18 mm TD-NMR system based on an upgraded Oxford QP20 which has been operated with a
Resonance Systems Spin Track pulsed TD-NMR spectrometer. We also operate a 10 mm Portable
Spin Track TD-NMR spectrometer from resonance Systems Ltd. The Spin Track NMR
also has multi frequency ability from 2 to 60 MHz and also operates an NMR
surface sensor. We also operate three Cosa-Xentaur Spin-Pulse TD-NMR spectrometers at 15 MHz (40 mm
sample dimension), 18 MHz (20 mm sample dimension), and 23 MHz (10 mm sample
dimension). These Cosa-Xentaur Spin-Pulse
spectrometers are manufactured in the United States and PNA is currently under
contract to assist in marketing and application development for this NMR
platform.
Other Analytical Equipment - Mid-IR ATR and Simulated Distillation GC
System:
- FTIR-ATR: Smiths Detection IdentifyIR - PNA is under contract with
Cosa-Xentaur to develop chemometric applications for the Smiths Detection
FTIR-ATR platform
- Simulated Distillation GC: Shimadzu GC-2010
- Micro-ESR Spectrometer
- Petrometrix NIR Spectrometer
- Karl-Fischer Moisture Analyzer
General Laboratory Equipment:
Process NMR Associates is equipped with various peripheral lab equipment to
facilitate the safe and effective preparation of NMR samples in 5mm and 10 mm
NMR tubes. These facilities include explosion proof refrigerator and oven, a
ductless fume hood, various sample prep equipment for NMR. We have a Virtis
benchtop freeze dryer for observation of low concentration components after
reconsitution in D2O.
NMR and Chemistry Related Library and Software:
Process NMR Associates has developed a 100+ volume NMR library containing most
published NMR books and references. We also have several
1H, 13C and
31P
assignment libraries for structural elucidation studies. The Sadtler C-Search
software is available on the Varian-300 spectrometer, ACD H-NMR is available
on PC. We have a rather extensive collection of chemistry, petroleum and
petrochemical related volumes as well as an entire set ASTM standards and
practices. We use Mnova 7.1, Acorn Nuts, Spinworks, and MestreC as post-processing
software when necessary.
Chemometrics Software:
Process NMR Associates uses the following chemometrics packages for method
development:
-
Grams with PLS/IQ - Galactic Industries
- Pirouette - Infometrix
- Matlab with Chemometric Toolbox from Eigenvector Research
- Eigenvector Research Solo 6.5
Anatomy of a Process NMR Spectrometer
For more details of our
capabilities contact John Edwards,
Tel: +1 (203) 744-5905 |
